“Without methylation there would be no life as we know it.” - C. Cooney 


What is methylation?

Methylation is the production of methyl groups which your body needs for a healthy life. It is the “central control dial of life.” Methyl groups turn your body systems on and off and help it function properly.


Why methylation matters and how methylated vitamins support it

Your body takes the food you eat and converts it into methyl groups. This takes time and energy and, sometimes, your body can’t do this properly, especially if you are under stress. But, you can support or even bypass this process. When you take methylated vitamins, your body doesn’t have to work hard to change the vitamins or food you eat into a version with methyl groups. That’s because methylated vitamins come with methyl groups attached and ready to go.

Best Nest Wellness supplements are made with methylated vitamins like methylfolate (B9), methylcobalamin (B12), and pyridoxal-5-phosphate (B6), the active form of vitamins found in your body that come with attached methyl groups. Having extra methyl groups can help your body work efficiently. 


But what are the benefits of methylated vitamins?

Proper methylation compensates for the DNA variations you were born with. It is one of the tools you have to change your genetic destiny. Optimal methylation can lead to support for :

  • Neuro-development
  • Memory 
  • Mood 
  • Focus 
  • Sleep 
  • Energy
  • Immunity 

It is important to all aspects of your physical, mental, and emotional health via hormone and neurotransmitter production and gene expression (turning genes on and off).


With poor methylation, your brain, gut, and liver can be affected. Many consequences are attributed to it, as well:

  • Fatigue
  • Brain fog
  • Mild depression
  • Mild anxiety
  • And more

How does the MTHFR gene variation affect methylation?

Stress, lack of sleep, and age are some of the reasons why your methyl groups may be depleted. In addition, if you have the MTHFR gene variant (affects approximately 60% of people) then your body is not making enough enzymes for methylation. As a result, you have fewer methyl groups in your body ready to be called into action. So, it is critically important for you to take methylated vitamins to boost your stores up.

Methylation affects your immune system health

Your body takes the food you eat and converts it into methyl groups. This takes time and energy and, sometimes, your body can’t do this properly. You can shortcut this process when you take methylated vitamins; with them, your body isn’t required to work extra hard to change the vitamins or food you eat into a version with methyl groups. That’s because methylated vitamins come with methyl groups attached and ready to go.

Having extra methyl groups at your immune system’s disposal can help it work efficiently without wearing you down. 

You can find methylated vitamins in our entire multivitamin line, including Multi+ line, Prenatal Multi+ line, and our Fertility line. If you need even more methyl support, we’ve got you covered with Smart Folate®.

Our supplements are made with methylated vitamins like methylfolate (B9), methylcobalamin (B12), and pyridoxal-5-phosphate (B6), the active form of nutrients found in your body.

 
Madhavi Gupta, MD

Madhavi Gupta, MD

Madhavi Gupta, MD is the founder and CEO of Best Nest Wellness. Dr. Gupta is a board-certified neurologist and has won The People’s Choice Award as a favorite doctor three years in a row. She holds a degree in biochemistry and humanities from MIT, completed her neurology residency in New York City, and completed her fellowship in headache medicine at Thomas Jefferson University Hospital.